超声表观积分背散射系数与骨矿密度的相关性分析

Correlation analysis between ultrasonic apparent integral backscatter coefficient and bone mineral density

摘要: 用超声评价骨质状况是近年来骨质疏松诊断方面的研究热点之一。介绍了超声背散射法及其参量表观积分背散射系数(Apparent Integral Backscatter coefficient,AIB)的测量及与骨矿密度(Bone Mineral Density,BMD)的相关性研究。在体采集了1087位志愿者跟骨的超声背散射信号,并用双能X射线骨密度仪(Dual X-ray Absorptiometry,DXA)测得腰椎和髋骨的BMD值,然后对AIB与BMD进行相关性分析。实验结果表明,参数AIB与BMD显著相关(R=0.58～0.64,n=1087,p<0.05),可被应用于松质骨状况评价。

Abstract: The study of ultrasonic assessment of bone status has been a hotspot in the diagnosis of osteoporosis recently. This paper focuses on the correlation analysis between ultrasonic apparent integral backscattering coefficient (AIB) and bone mineral density (BMD). A custom ultrasonic backscatter system was employed to investigate the calcaneus of 1087 volunteers in vivo. The BMD of the volunteers were measured from the spine and hip by the dual X-ray absorptiometry (DXA). The results show that the AIB is obviously correlated to the BMD (R=0.58～0.64, n=1087, p<0.05). Thus, the AIB of ultrasonic backscattering signals can be used to assess the status of cancellous bone.