Abstract: As one of the sterilization method,ultrasound has received much research attention. Ultrasound alone can have a good sterilization effect. However,if ultrasound is used in industrial settings and required to kill bacteria at a high rate,very high ultrasonic power is needed,consuming a great deal of energy. In other words,as a means of sterilization,ultrasound alone is too expensive to be used in the industrial en-vironment. Nonetheless,when used in conjunction with other sterilization technique,the effect of ultras-onic cavitation can improve the efficiency of other sterilization techniques,and energy used for the ultra-sound is much lower. The results of this study show that combination of ultrasound and other technique can be used effectively for sterilization.