Study on ultrasound enhanced extraction of the total flavonoid from Plantago

A novel extraction process of the total flavonoid from Plantago by ultrasound has been studied.The optimum extracting conditions of the total flavonoid are investigated by using orthogonal experimental design.The significance of these factors affecting the total flavonoid is in the following order:extraction temperture>ultrasound power>ultrasound time>solid/liquid ratio.The optimal parameters are:solid/liquid ratio 1:20 g/mL,ultrasound extraction time 30min,extraction temperature 50℃,ultrasound power 200W.Under this optimal condition,the extraction rate of flavonoid is 0.645%.Compared with conventional extraction,it is more effective with advantages in short extraction period,higher yield and saving solvent amount.